• Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder 

      McCarthy, Michael J.; Stautland, Andrea; Jakobsen, Petter; Ødegaard, Ketil Joachim; Andreassen, Ole Andreas; Djurovic, Srdjan; Morken, Gunnar; Schøyen, Helle Kristine; McInnis, Melvin G.; Alda, Martin; Gage, Fred H.; Calabrese, Joseph R.; Zandi, Peter P.; Nievergelt, Caroline M.; Shilling, Paul D.; Kelsoe, John R. (Peer reviewed; Journal article, 2019)
      Bipolar disorder (BD) is a serious mood disorder associated with circadian rhythm abnormalities. Risk for BD is genetically encoded and overlaps with systems that maintain circadian rhythms. Lithium is an effective mood ...
    • Clinical predictors of non-response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study 

      Lin, Yan; Maihofer, Adam X.; Stapp, Emma; Ritchey, Megan; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H; Bertram, Holli; Bhattacharjee, Abesh; Calkin, Cynthia V.; Conroy, Carla; Coryell, William; D´Arcangelo, Nicole; DeModena, Anna; Biernacka, Joanna M.; Fisher, Carrie; Frazier, Nicole; Frye, Mark; Gao, Keming; Garnham, Julie; Gershon, Elliot; Glazer, Kara; Goes, Fernando S; Goto, Toyomi; Karberg, Elizabeth; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; Stautland, Andrea; McCarthy, Michael J.; McInnis, Melvin G.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Ødegaard, Ketil Joachim; Syrstad, Vigdis Elin Giæver; Ryan, Kelly; Schinagle, Martha; Schøyen, Helle Kristine; Andreassen, Ole; Shaw, Martha; Shilling, Paul D.; Slaney, Claire; Tarwater, Bruce; Calabrese, Joseph R.; Alda, Martin; Nievergelt, Caroline M.; Zandi, Peter P.; Kelsoe, John R. (Journal article; Peer reviewed, 2021)
      Background Lithium is regarded as a first-line treatment for bipolar disorder (BD), but partial response and non-response commonly occurs. There exists a need to identify lithium non-responders prior to initiating treatment. ...
    • Complexity and variability analyses of motor activity distinguish mood states in Bipolar Disorder 

      Jakobsen, Petter; Stautland, Andrea; Riegler, Michael; Côté-Allard, Ulysse Teller Masao; Sepasdar, Zahra; Nordgreen, Tine; Tørresen, Jim; Fasmer, Ole Bernt; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2022)
      Changes in motor activity are core symptoms of mood episodes in bipolar disorder. The manic state is characterized by increased variance, augmented complexity and irregular circadian rhythmicity when compared to healthy ...
    • Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis 

      Niemsiri, Vipavee; Rosenthal, Sara Brin; Nievergelt, Caroline M.; Maihofer, Adam X.; Marchetto, Maria C.; Santos, Renata; Shekhtman, Tatyana; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H.; Bertram, Holli; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Conroy, Carla; Coryell, William H.; DeModena, Anna; Eyler, Lisa T.; Feeder, Scott; Fisher, Carrie; Frazier, Nicole; Frye, Mark A.; Gao, Keming; Garnham, Julie; Gershon, Elliot S.; Goes, Fernando S.; Goto, Toyomi; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; McCarthy, Michael J.; McInnis, Melvin G.; Craig, David; Millett, Caitlin E.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Donovan, Claire O’; Ødegaard, Ketil Joachim; Ryan, Kelly; Schinagle, Martha; Shilling, Paul D.; Slaney, Claire; Stapp, Emma K.; Stautland, Andrea; Tarwater, Bruce; Zandi, Peter P.; Alda, Martin; Fisch, Kathleen M.; Gage, Fred H.; Kelsoe, John R. (Journal article; Peer reviewed, 2023)
      Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this study is to identify functional genes and ...
    • HYPERAKTIV: An Activity Dataset from Patients with Attention-Deficit/Hyperactivity Disorder (ADHD) 

      Hicks, Steven; Stautland, Andrea; Fasmer, Ole Bernt; Førland, Wenche; Hammer, Hugo Lewi; Halvorsen, Pål; Mjeldheim, Kristin; Ødegaard, Ketil Joachim; Osnes, Berge; Syrstad, Vigdis Elin Giæver; Riegler, Michael; Jakobsen, Petter (Chapter, 2021)
      Machine learning research within healthcare frequently lacks the public data needed to be fully reproducible and comparable. Datasets are often restricted due to privacy concerns and legal requirements that come with ...
    • Reduced heart rate variability during mania in a repeated naturalistic observational study 

      Stautland, Andrea; Jakobsen, Petter; Fasmer, Ole Bernt; Osnes, Berge; Tørresen, Jim; Nordgreen, Tine; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2023)
      Background: Bipolar disorder (BD) is a chronic recurrent mood disorder associated with autonomic nervous system (ANS) dysfunction, indexed by heart rate variability (HRV). Changes in HRV between mood states are sparsely ...